General articles

    Dr. Karam Lokendro, MD    

Vitiligo is a common, acquired pigmentary disorder, characterized by variable-sized depigmented patches, of unknown etiology affecting 1-2% of world population without any racial, geographic or sexual predilection. The course of disease is chronic, and often progressive.It is a cause of severe psychosocial distress in most of the patients. This article aims to give an overview of [...]

Introduction: Vitiligo denotes an acquired primary, usually progressive, melanocytopenia of unknown etiology, clinically manifested by circumscribed achromic maculus often associated with leukotrichia and histologically by degeneration and disappearance of melanocytes in the involved skin and not infrequently in the pigment epithelium of the eyes, leptomeninges and inner ear.  For treatment of vitiligo, skin colour and ability [...]

Vitiligo is an acquired common depigmenting disorder characterized by development of depigmented macules and patches secondary to selective destruction of melanocytes. The prevalence of vitiligo is high ranging from 0.005 to 0.38% cases worldwide. The etiological factors of vitiligo are complex including genetic, immunological, neurohormonal, cytotoxic, oxidative stress and melanocytorrhagy. Most of the currently available evidence [...]

First of all, we have to bring the Vitiligo patients a stable Vitiligo. A stable Vitiligo is a condition where the patient is not having new lesions or extension of existing lesion for the last 9 months. After stabilising patient , dermato-surgery can be taken up. The followings are the Surgical methods available : 1.    Punch [...]

In vitiligo, a faulty immune reaction kills off pigment cells called melanocytes and leaves patches of white skin. Considered an autoimmune disorder, vitiligo often emerges in adolescence or later, occurring in an estimated 1 to 2 percent of the world’s population and affecting all ethnic groups equally — although the depigmentation is more obvious on darker [...]

Vitiligo is a disorder of the skin pigmentation characterized by well-defined, ivory white macular lesion. It affects 1% of the population worldwide. Both sexes are equally affected. In 10-20% of people, vitiligo goes on its own. However, in majority of the patient the condition tends to worsen with time. Vitiligo is often confused with leprosy by common people [...]

Each cell of human body has 23 pairs of chromosomes. Genes are DNA proteins containing specific set of instructions for our body. Each gene has a specific location on our 23 chromosomes. One copy of each pair of chromosomes  from each of our parents is inherited to our children. 22 pairs of chromosomes are known as [...]