Vitiligo leinasi karamna karidagi oihanlakpano haiba houjikphaobagi oinadi tasengna khangdari.Thajanaba,oithokani khanba kaya amadi lei.Website simaki atopa page kayadasu kupna neinari.Pari puri gi samnarakpa,autoimmune system gi akaiba,neuronal dysregulation,oxidative stress,cytotoxic to various substances,melanocytorragy na chingba kaya ama neinari.Adubu khwaidagi henna thajanaba Vitiligogi hourakphamdi,autoimmunity amadi genetic(pari purigi) oiba hiramsingsini.Masiga loinana hena thajanaba maramdi,Vitiligo haiba leina ashi,leina makhal kharana punshanlaga oihanlakpa laiongni.Aduna houjikphaobagi oinadi Vitiligo gi hourakphamsi,chamamnari,ashengba khandari.
Vitiligo na naraba meyoi kayada,nungi oiba atopa leina kaya ama loinaba yai.Hiramsida ehan hanba oina Thomas Addision na ,ingshok 1855 da phongdoklamkhi.Mahakna Vitiligo ga Adrenal gland gi mathouda sontharaklaba anaba 13 gi manungda ,meyoi amada Vitiligo naba thengnakhi.Ingshok 1960 gi aduyaidagi ahanba oina,autoimmune gi akaiba amadagi Vitiligo oihanlapani haibagi paodam lei.Matung tarakpa oina hiramsida paodam kaya ama thengnei.
Matung tarakpada,autoimmunity ga mari leinaba leina kaya amaga Vitiligo ga punna naminaba anaba kaya thengnarakpagi,paodamlaklea.
THYROID KI ANABA:
Ahanba oina Cunliffe amadi mahaka loinaba singns ingshok 1968 da Thyroid ki anabaga Vitiligo ga loinabagi paodamlakhi.Matung tarakpadasu atopa scientist kayana Thyroid gi anaba makhal animak haibadi hyperthyroidism(thyroid gi awangba anaba) amadi hypothyroidism(thyroidki anemba anaba) Vitiligo ga loinaba yai haibagi paodam kaya phonglakkhi.Vitiligo gi anabasingi manungda 15% gumbadi thyroid gi anabaga loinaba yai.Thyroid gi dysfuntion ,ayambana mapangal sonthahanba sing asi(hypothyroid),meyoi kayada autoimmunegi asoibadagi thokhanli.Maram asinasu Vitiligo ashi autoimmune gi akaibadagi oihanlakpa yai habasigi thajabasi henna chetsanhanli.
DIABETES MELLITUS:
Diabetes mellitus gi hourakphamsu mapung phana sugaina khangdribagumbani.Diabetes na naraba meyoiba kayada autoimmune gi asoibadagi houraktuna,Pancrease da yaoriba islet of Langerhans bu manghan takhanbadagi leina ashi oirakpani haibagi khudam kaya paodam lei.Vitiligo gi anabasingda Diabetis mellitus ga loinabasi,Vitiligo na nadaba singdagi khara hena thengnei.
VITILIGO AMASUNG EGI MARAMGI LEINA:
Leukaemias,lymphomas na naraba singda Vitiligo naba ashi khara toina thengnei.HIV/AIDS patient singda Vitiligo nabagi chang ,achamba miyamdagi hena thengnei haibagi paodam lei.Matangsida khngjanba yaba waphamdi,leukaemias,lymphomas amadi AIDS,loinamak autoimmunity gi akaiba(dysregulation) loinaba ngaktani.Leinasing ashina antibodies amadi Cytotoxic lymphocytes(hingchabagi sakti chenba lymphocytes) puthoktuna,unshagi kuchu sunglakliba Melanocytes sing manghan takhankhiba amadi hatokiba oihanlamba yabagi paodamsing lei.
GLAND MAYAM AMA PUNA AKAIBA THORAKPA(POLYGANDULAR DYSFUNCTION):
Polyglandular dysfuntiona naraba meyoi kayada Vitiligo nabagi paodamsing lei.Polyglandular dysfunction haiba leina ashi makti yamna hena sathiba,mashing yamlaba,endocrine glands(hormone sungliba gland sing) kaya ama asum asum sitharakpani.Thyroid,pancreas,adrenal glands,gonads,na chingba khuijanlakle amadi sihanlake.Chromosome no.21 ga marileinaba autoimmunegi oiba sathiba leinani.Karigumbada,endocrine gland nataba,atopa gland/organ singdasu,autoimmune gi akaibasina attack tourakpa yai.Masina maram oiduna,Melanocytes tasu sithahanabagi machak ama oiramba yai haiba thajaba lei.
ATOPA MAYANTUYAN GI LAINA KHARA:
Vitiligo ga loinana thengnaganba leina khara sing,samjabi(alopacea areata),psoriasis,Khujil khuyagi asoibasing,Collagen vascular disorders,lichen planus,dermatitis herpetiformis,central nervous system abnormalities na chingbani.Makhoising ashi tanja charubanara natraga tasengna leina loinaba yabagi maramsing leibara haibadudi hangba yaba waphamsing oiri.Maramdi prithibi gi oina meyoi 40 millions gumba da Vitiligo na nai.
Aroibada hainingbadi,Vitiligo gi ashengba hourakpham khangdribana,nunggi oiba leinasing Vitiligo ga loinabagi hiramsisu adum chayetnaba khangdaba kaya ama leiri.
Dr. Karam Lokendro, MD
Sir n khangba da kanaraba myam am phongdokpibgi yam haraojei wakhal d chamanaba kya am leirambsu khra makti kokpa ngame.Sir bu thagatchari.